Granutol™
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Application
Granutol™ is a D-mannitol Filler for direct compression developed by applying our technology accumulated with Dilactose™ (lactose for direct compression).
Since it is superior to lactose it offers a sense of comfort when taking medicine, and is suitable as a Filler for orally disintegrating tablets and chewable tablets.
FEATURE
- 100% D-mannitol granules comprised of stable β-form crystals
There are three types of D-mannitol crystal forms known as α-form, β-form, and δ-form.
Among them, β-form is said to be the most stable. - Useful for tableting drugs that are unstable with moisture and drugs that easily cause Maillard reaction
Because of 100% D-mannitol granules, this is chemically stable, with almost no free water.
Therefore, it can also be used for reactive drugs. - High formability and fluidity that provide an optimum solution for direct compression
With high formability and fluidity, it provides an optimum solution as a Filler for direct compression. - Suitable as a Filler for orally disintegrating tablets and chewable tablets because it offers a sense of comfort when taking medicine.
Mannitol, with moderate sweetness and a refreshing sensation, is excellent because it offers a sense of comfort when taking medicine.
Tablets that disintegrate quickly in the oral cavity can be obtained in combination with an appropriate amount of disintegrants.
Grade F in particular, which is excellent in formability and disintegrability, provides an optimum solution for orally disintegrating tablets.
- 100% D-mannitol granules comprised of stable β-form crystals
PACKING FORM
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Product Internal volume Outside packaging Inside packaging Granutol™R 20 kg Cardboard box Polyethylene bag Granutol™S 20 kg Cardboard box Polyethylene bag Granutol™F 20 kg Cardboard box Polyethylene bag
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